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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Validate Clinical Trial Data Reporting | 20% | - Programming validation techniques - Use PROC COMPARE and log review - Validation principles |
| Clinical Trials Process | 5% | - Clinical trial lifecycle and protocol - Derive programming requirements from protocol and CRF |
| Transform or Summarize Clinical Trials Data | 15% | - Aggregation and transposition - Derive variables and study days - Data step manipulation |
| Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
| Clinical Trials Data Structures | 10% | - Define.xml and dataset specifications - Clinical domain structures - CDISC standards: SDTM, ADaM |
| Macro Programming for Clinical Trials | 15% | - Create and call macros - Macro variables and parameters - Debugging macros |
| Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
| Manage Clinical Trials Data | 5% | - Use SQL and dictionary tables - Clean, merge, and subset data - Access and explore clinical datasets |
| Regulatory Submissions | 5% | - ICH and FDA guidelines - Compliance for clinical data reporting |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
1. The following SAS program is submitted:
Which types of variables are DayofMonth, MonthofYear, and Year?
A) DayofMonth and Year are numeric. MonthofYear is character
B) DayofMonth, Year, and MonthofYear are numeric.
C) DayofMonth, Year, and MonthofYear are character.
D) DayofMonth, Year, and MonthofYear are date values
2. The following partial output was produced from the SAS Dictionary Tables.
Which SQL statement produced this output?
A) proc sql;
select scope, name from dictionary.macros
where scope = 'GLOBAL';
quit;
B) proc sql;
select * from dictionary.macros
where scope = 'global';
quit;
C) proc sql;
select * from dictionary.macros
where scope = 'GLOBAL';
quit;
D) proc sql;
select scope, name from dictionary.macros
where scope = 'global';
quit;
3. A Statistical Analysis Plan defines study day as the number of days between the visit date and the date of randomization plus one day.
The following SAS program is submitted using a macro from the project's library:
How is the STUDYDAY macro defined?
A) %MACRO studyday(rand, visit);
&vdt. ?&rdt. + 1
%MEND studyday;
B) %MACRO studyday(rand=, visit=);
&vdt. ?&rdt. + 1
%MEND studyday;
C) %MACRO studyday(visit=, rand=);
&visit. ?&rand. + 1
%MEND studyday;
D) %MACRO studyday(rand, visit);
&visit. ?&rand. + 1
%MEND studyday;
4. Given the following complete dataset (WORK.TESTDM) with the variables USUBJID (character) and AGE (numeric):
The following code is executed:
proc sql;
select age into: age separated by ','
from testdm;
quit;
What is the value of the macro variable AGE?
A) Blank, the code will not execute
B) 17.1,17.7,4.4,3.8,6.3
C) 17.1 17.7 4.4 3.8 6.3
D) 17, 17, 4, 3, 6
5. Where would you store a value collected on a case report form but not defined in an SDTM domain?
A) RELREC
B) SUPPQUAL
C) SC
D) DM
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: A | Question # 3 Answer: D | Question # 4 Answer: B | Question # 5 Answer: B |
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