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ASCP ASCP-MLT Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Laboratory Operations | 5-10% | - Laboratory mathematics and instrumentation - Pre-analytical, analytical, and post-analytical processes - Laboratory safety and regulatory compliance - Quality control and quality assurance |
| Immunology and Serology | 5-10% | - Infectious disease serology - Immunologic testing methodologies - Immune system principles and components - Autoimmune and immunodeficiency disorders |
| Urinalysis and Other Body Fluids | 5-10% | - Cerebrospinal, serous, and synovial fluids - Urine formation and composition - Semen and amniotic fluid testing - Physical, chemical, and microscopic analysis |
| Hematology | 20-25% | - Hemostasis and coagulation testing - Routine and automated hematology procedures - White blood cell morphology and diseases - Red blood cell physiology and disorders |
| Blood Banking (Immunohematology) | 15-20% | - Blood group systems and antigens - Transfusion reactions and adverse events - Blood components and storage - Antibody detection and identification - Compatibility testing |
| Clinical Chemistry | 20-25% | - Toxicology and liver/kidney function tests - Endocrinology and therapeutic drug monitoring - Carbohydrates, lipids, proteins, and enzymes - Electrolytes, acid-base balance, and blood gases |
| Microbiology | 15-20% | - Identification of pathogenic microorganisms - Specimen collection and culture techniques - Bacteriology and antimicrobial susceptibility - Mycology, parasitology, and virology |
ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:
A positive RPR test and a negative FTA-ABS test is most likely the result of:
- A. Latent syphilis
- B. False positive reaction
- C. Secondary syphilis
- D. Primary syphilis
Correct Answer: B 🗳️
The MCV is indicative of microcytosis with MCV=<80fL. The RDW is within normal limits and indicative of a homogenous cell population.
If the MCV was >100 fL, this would be indicative of macrocytosis. An RDW that was outside of normal limits would be indicative of a heterogenous cell population.
An 18 year old female has a CBC as part of a routine physical exam. The following results were obtained and the physician determines she is anemic. After reviewing her CBC results shown below, which of the following would be an appropriate description of the anemia?
White blood cells (WBC): 5.6 x 10^9/L (RR:4.0-10.0 x 10^9/L)
Red blood cells (RBC): 3.7 x 10^12/L (RR: 4.2-5.9 x 10^12/L)
Hemoglobin: 9.9 g/dL (RR:12-16 g/dL)
Hematocrit: 28% (RR: 37-48%)
MCV: 75 fL (80-100 fL)
RDW-CV: 14% (RR: 11.0-15.0%)
- A. Macrocytic, heterogenous
- B. Microcytic, homogenous
- C. Microcytic, heterogenous
- D. Macrocytic, homogenous
Correct Answer: B 🗳️
Since cimetidine inhibits CYP2D6, less amphetamine will probably need to be given since it will not be able to be metabolized as readily.
Most drug interactions are like this: one drug inhibits or competes with the same CYP450 as another drug. The end result is that higher concentrations of one, or both, drugs are present, leading to potential toxicity.
A patient is taking cimetidine for a stomach ulcer. This drug inhibits CYP2D6. The patient is now prescribed amphetamine for narcolepsy. Amphetamine is metabolized by CYP2D6. What would you predict?
- A. The dose for amphetamine needs to be higher than normal.
- B. The dose for the amphetamine needs to be lower than normal.
- C. The two drugs can never be given together since they interact.
- D. Nothing can be assumed until you know the patient's status (PM, EM, UM).
Correct Answer: B 🗳️
Blood plasma will contain coagulation proteins, but not in a clotted tube where serum is present.
Blood serum contains each of the following substances except:
- A. Coagulation proteins
- B. Sugars
- C. Water
- D. Electrolytes
Correct Answer: A 🗳️
What are the certification requirements for clinical laboratory professionals?
- A. college degree
- B. college degree and a national certification exam
- C. national certification exam
- D. on the job training
Correct Answer: B 🗳️
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